Super Short Summary

Empire of Pain by Patrick Radden Keefe explores the origins of the opioid crisis through the story of the Sackler family and Purdue Pharmaceuticals, detailing their roles in the creation and aggressive marketing of OxyContin despite growing evidence of its addictive potential and misuse. It traces the family's rise from the humble beginnings of the Sackler brothers to their influence in medical advertising, philanthropy, and the controversial expansion of opioid use for pain management, ultimately leading to legal and public scrutiny. Descriptions of living with opioid use disorder, including overdoses and deaths by suicide, are present in the narrative.