Super Short Summary

In Plagues and Peoples, William H. McNeill explores how disease patterns have significantly influenced human history from prehistory to modern times, emphasizing the interdependence between humans and microparasites. Starting from 100,000 years ago in sub-Saharan Africa, McNeill charts the co-evolution of humans and diseases through the agricultural revolution, the rise of civilizations, global trade, and technological advances. He asserts that while humanity has made significant strides in combating diseases, vulnerability to new parasitic invasions remains. The narrative acknowledges the heavy toll of diseases on populations, especially in the Americas during European colonization.